+1 814 865 1740 eam7@psu.edu

Publications

Book Chapters

A Bug’s Life in another Bug.

Yamada, R., Brownlie, J., McGraw, E.A., O’Neill, S.L., 2007, Insights into Wolbachia biology provided through genomic analysis, in Wolbachia: A Bug’s Life in another Bug, eds Hoerauf, A and Rao, RU, Karger, Basel Switzerland, pp. 77-89. Doi: 10.1159/000104245 

Journal Articles

Larval crowding enhances dengue virus loads in Aedes aegypti, a relationship that might increase transmission in urban environments.

Dutra, H.L.C., Marshall, D.M., Comerford, B., McNulty, B.P., Diaz, A.M., Jones, M.J.J., Mejia, A.J., Bjornstad, O.N., McGraw, E.A. 2024. Larval crowding enhances dengue virus loads in Aedes aegypti, a relationship that might increase transmission in urban environments. PLOS Negl Trop Dis. Doi:10.1371/journal.pntd.0012482

The mechanism of cytoplasmic incompatibility is conserved in Wolbachia-bearing Aedes aegypti mosquitoes deployed for arbovirus control.

Kaur, R. Meier, C.J., McGraw, E.A., Hillyer, J.F., Bordenstein, S.R. 2024. The mechanism of cytoplasmic incompatibility is conserved in Wolbachia-bearing Aedes aegypti mosquitoes deployed for arbovirus control. PLOS Biology. 22:e3002573. Doi:10.1371/journal.pbio.3002573

Alpha-mannosidase-2 modulates arbovirus infection in a pathogen- and Wolbachia-specific manner in Aedes aegypti mosquitoes.

Urakova, N., Joseph, R.E., Huntsinger, A., Macias, V.M., Jones, M.J., Sigle, L.T., Li, M., Akbari, O.S., Xi, Z., Lymperopoulos, K., Sayre, R.T., McGraw, E.A., Rasgon, J.L. 2024. Alpha-mannosidase-2 modulates arbovirus infection in a pathogen- and Wolbachia-specific manner in Aedes aegypti mosquitoes. Insect Mol Biol. 33:362-371. Doi:10.1111/imb.12904

Phenotypic adaptation to temperature in the mosquito, Aedes aegypti.

Dennington, N.L., Grossman, M.K., Ware-Gilmore, F., Teeple, J.L., Johnson, L.R., Shocket, M.S., McGraw, E.A., Thomas, M.B. 2024. Phenotypic adaptation to temperature in the mosquito, Aedes aegypti. Glob Chang Biol. 30:e17041. Doi:10.1111/gcb.17041

Jamestown Canyon Virus is transmissible by Aedes aegypti and is only moderately blocked by Wolbachia co-infection.

Lau, M., Dutra, H.L.C., Jones, M.J., McNulty, B.P., Diaz, A.M., Ware-Gilmore, F., McGraw, E.A. 2023. Jamestown Canyon Virus is transmissible by Aedes aegypti and is only moderately blocked by Wolbachia co-infection. PLOS Negl Trop Dis 17: e0011616. Doi:10.1371/journal.pntd.0011616

Exposure to ultraviolet-B radiation increases the susceptibility of mosquitoes to infection with dengue virus.

Alton, L.A., Novelo, M., Beaman, J.E., Arnold, P.A., Bywater, C.L., Kerton, E.J., Lombardi, E.J., Koh, C., McGraw, E.A. 2023. Exposure to ultraviolet-B radiation increases the susceptibility of mosquitoes to infection with dengue virus. Glob Chang Biol 9(19):5540-5551. Doi:10.1111/gcb.16906

Dengue and chikungunya virus loads in the mosquito Aedes aegypti are determined by distinct genetic architectures.

Novelo, M., Dutra, H.L.C., Metz, H.C., Hall, M.J., Sigle, L.T., Frentiu, F.D., Allen, S.L., Chenoweth, S.F., McGraw, E.A. 2023. Dengue and chikungunya virus loads in the mosquito Aedes aegypti are determined by distinct genetic architectures. PLOS Pathog 19:e1011307. Doi:10.1371/journal.ppat.1011307

Assessing the role of family level variation and heat shock gene expression in the thermal stress response of the mosquito Aedes aegypti.

Ware-Gilmore, F., Novelo, M., Sgrò, C.M., Hall, M.D., McGraw, E.A. 2023. Assessing the role of family level variation and heat shock gene expression in the thermal stress response of the mosquito Aedes aegypti. Phil Trans R Soc B 378:20220011. Doi:10.1098/rstb.2022.0011

Attempts to use breeding approaches in Aedes aegypti to create lines with distinct and stable relative Wolbachia densities.

Mejia, A.J., Jimenez, L., Dutra, H.L.C., Perera, R., McGraw, E.A. 2022. Attempts to use breeding approaches in Aedes aegypti to create lines with distinct and stable relative Wolbachia densities. Heredity. doi:10.1038/s41437-022-00553-x

Cross-tissue and generation predictability of relative Wolbachia densities in the mosquito Aedes aegypti.

Mejia, A.J., Dutra, H.L.C., Jones, M.J., Perera, R. McGraw, E.A. 2022. Cross-tissue and generation predictability of relative Wolbachia densities in the mosquito Aedes aegypti. Parasites Vectors 15, pp 128. Doi:10.1186/s13071-022-05231-9

Microbes increase thermal sensitivity in the mosquito Aedes aegypti, with the potential to change disease distributions.

Ware-Gilmore, F., Sgrò, C.M., Xi, Z., Dutra, H.L.C., Jones, M.J., Shea, K., Hall, M.D., Thomas, M.B., McGraw, E.A. 2021. Microbes increase thermal sensitivity in the mosquito Aedes aegypti, with the potential to change disease distributions. PLOS Neglected Tropical Diseases. Doi:10.1371/journal.pntd.0009548

The effects of DENV serotype competition and co-infection on viral kinetics in Wolbachia-infected and uninfected Aedes aegypti mosquitoes.

Novelo, M., Audsley, M.D., McGraw, E.A. 2021. The effects of DENV serotype competition and co-infection on viral kinetics in Wolbachia-infected and uninfected Aedes aegypti mosquitoes. Parasites Vectors 14, pp 314. Doi:10.1186/s13071-021-04816-0

Transmission and protection against re-infection in the ferret model with the SARS-CoV-2 USA-WA1/2020 reference isolate.

Patel, D.R., Field, C.J., Septer, K.M., Sim, D.G., Jones, M.J., Heinly, T.A., Vanderford, T.H., McGraw, E.A., Sutton, T.C.2021. Transmission and protection against reinfection in the ferret model with the SARS-CoV-2 USA-WA1/2020 reference isolate. Journal of Virology. 95:e02232-20. Doi:10.1128/JVI.02232-20

Temperature modulates immune gene expression in mosquitoes during arbovirus infection.

Randika Wimalasiri-Yapa, B.M.C., Barrero, R.A., Stassen, L., Hafner, L.M., McGraw, E.A., Pyke, A.T., Jansen, C.C., Suhrbier, A., Yakob, L., Hu, W., Devine G.J., Frentiu, F.D. 2021. Temperature modulates immune gene expression in mosquitoes during arbovirus infection. Open Biology 11. Doi:10.1098/rsob.200246

Transinfection of buffalo flies (Haematobia irritans exigua) with Wolbachia and effect on host biology.

Madhav, M., Brown, G., Morgan, J.A.T., Asgari, S., McGraw, E.A., James, P. 2020. Transinfection of buffalo flies (Haematobia irritans exigua) with Wolbachia and effect on host biology. Parasites Vectors 13, pp 296. Doi:10.1186/s13071-020-04161-8

Dengue virus dominates lipid metabolism modulations in Wolbachia-coinfected Aedes aegypti.

Koh, C., Islam, M.N., Ye, Y.H., Chotiwan, N., Graham, B., Belisle, J.T., Kouremenos, K.A., Dayalan, S., Tull, D.L., Klatt, S., Perera, R., McGraw, E.A. 2020. Dengue virus dominates lipid metabolism modulations in Wolbachia-coinfected Aedes aegypti. Communications Biology 3, 518. Doi:10.1038/s42003-020-01254-z

Artificial Selection Finds New Hypotheses for the Mechanism of Wolbachia-Mediated Dengue Blocking in Mosquitoes

Ford, S.A., Albert, I., Allen, S.L., Chenoweth, S.F., Jones, M., Koh, C., Sebastian A., Sigle, L.T., McGraw, E.A. 2020. Artificial Selection Finds New Hypotheses for the Mechanism of Wolbachia-Mediated Dengue Blocking in Mosquitoes. Frontiers in Microbiology 11, pp 1456. Doi:10.3389/fmicb.2020.01456

Transinfection of buffalo flies (Haematobia irritans exigua) with Wolbachia and effect on host biology.

Madhav, M., Brown, G., Morgan, J.A.T. et al. Transinfection of buffalo flies (Haematobia irritans exigua) with Wolbachia and effect on host biology. Parasites Vectors 13, pp 296. Doi:10.1186/s13071-020-04161-8

Wolbachia successfully replicate in a newly established horn fly, Haematobia irritans irritans (L.) (Diptera: Muscidae) cell line.

Madhav, M., Brown, G., Morgan, J.A., Asgari, S., McGraw, E.A., Munderloh, U.G., Kurtti, T.J. and James, P. 2020. Wolbachia successfully replicate in a newly established horn fly, Haematobia irritans irritans (L.) (Diptera: Muscidae) cell line. Pest Management Science. doi:10.1002/ps.5785

Buffalo Flies Receptive to Wolbachia Infection: An Opportunity for Population Control?

Madhav, M., Brown, G., Morgan, J.A.T., Asgari, S., McGraw, E.A., James, P. 2019. Buffalo Flies Receptive to Wolbachia Infection: An Opportunity for Population Control? Proceedings 36, pp 79. doi:10.3390/proceedings2019036079

Infectious Diseases: Antiviral Wolbachia Limits Dengue in Malaysia.

Chrostek, E., Hurst, G.D.D., McGraw, E.A. 2020. Infectious Diseases: Antiviral Wolbachia Limits Dengue in Malaysia. Current Biology 30, pp 30-32. Doi:10.1016/j.cub.2019.11.046

Chikungunya Virus Transmission at Low Temperature by Aedes albopictus Mosquitoes.

Wimalasiri-Yapa, B.M.C.R., Stassen, L., Hu, W., Yakob, L., McGraw, E.A., Pyke, A.T., Jansen, C.C., Devine, G.J., Frentiu, F.D. 2019.  Chikungunya Virus Transmission at Low Temperature by Aedes albopictus Mosquitoes. Pathogens 8, pp 149. doi:10.3390/pathogens8030149

Selection on Aedes aegypti alters Wolbachia-mediated dengue virus blocking and fitness.

Ford, S.A., Allen, S.L., Ohm, J.R., Sigle, L.T., Sebastian, A., Albert, I., Chenoweth, S.F., McGraw, E.A. 2019. Selection on Aedes aegypti alters Wolbachia-mediated dengue virus blocking and fitness. Nature Microbiology. doi:10.1038/s41564-019-0533-3

Using genetic variation in Aedes aegypti to identify candidate anti-dengue virus genes.

Terradas, G and McGraw, E.A. 2019. Using genetic variation in Aedes aegypti to identify candidate anti-dengue virus genes. BMC Infectious Diseases 19, pp 580. doi:10.1186/s12879-019-4212-z

Huang, X., Hu, W., Yakob, L., Devine, G.J., McGraw, E.A., Jansen, C.C., Faddy, H.M, Frentiu,F.D. (2019) El Niño southern Oscillation, overseas arrivals and imported chikungunya cases in Australia: A time series analysis. PLoS Negl Trop Dis 13(5): e0007376. doi:10.1371/journal.pntd.0007376

Expanding the canon: Non-classical mosquito genes at the interface of arboviral infection.

Sigle, L.T., McGraw, E.A. 2019. Expanding the canon: Non-classical mosquito genes at the interface of arboviral infection. Insect Biochemistry and Molecular Biology. Doi:10.1016/j.ibmb.2019.04.004.

A Role for the Insulin Receptor in the Suppression of Dengue Virus and Zika Virus in Wolbachia-Infected Mosquito Cells.

Haqshenas, G., Terradas, G., Paradkar, P.N., Duchemin,J-B., McGraw, E.A., Doerig, C. 2018 A Role for the Insulin Receptor in the Suppression of Dengue Virus and Zika Virus in Wolbachia-Infected Mosquito Cells. Cell Reports 26, pp529-535.e3. Doi: 10.1016/j.celrep.2018.12.068

Complete genome of Aedes aegypti anphevirus in the Aag2 mosquito cell line.

Di Giallonardo F., Audsley, M.D., Shi M., Young P.R, McGraw E.A, Holmes E.C. 2018. Complete genome of Aedes aegypti anphevirus in the Aag2 mosquito cell line. Journal of General Virology. doi:10.1099/jgv.0.001079

Wolbachia enhances insect‐specific flavivirus infection in Aedes aegypti mosquitoes

Amuzu, H.E., Tsyganov , K., Koh, C., Herbert, R.I., Powell, D.R., McGraw, E.A. 2018. Wolbachia enhances insect‐specific flavivirus infection in Aedes aegypti mosquitoes. Ecology and Evolution. doi:10.1002/ece3.4066

Family level variation in Wolbachia-mediated dengue virus blocking in Aedes aegypti.

Terradas, G., Allen, S.L., Chenoweth, S.F., McGraw, E.A. 2017.Family level variation in Wolbachia-mediated dengue virus blocking in Aedes aegypti. Parasites & Vectors 10, pp622. doi:10.1186/s13071-017-2589-3

Wolbachia infection alters the relative abundance of resident bacteria in adult Aedes aegypti mosquitoes, but not larvae.

Audsley, M.D., Seleznev, A., Joubert, D.A., Woolfit, M., O’Neill, S.L. and McGraw, E.A. 2017. Wolbachia infection alters the relative abundance of resident bacteria in adult Aedes aegypti mosquitoes, but not larvae. Molecular Ecology. doi:10.1111/mec.14436

The nature of the immune response in novel Wolbachia-host associations.

Herbert, R.I., McGraw, E.A. 2017. The nature of the immune response in novel Wolbachia-host associations. Symbiosis, pp 1–12. Doi:10.1007/s13199-017-0503-6

The microbiome composition of Aedes aegypti is not critical for Wolbachia-mediated inhibition of dengue virus.

Audsley, M.D., Ye, Y.H., McGraw, E.A., 2017.The microbiome composition of Aedes aegypti is not critical for Wolbachia-mediated inhibition of dengue virus. PLoS Negl Trop Dis. doi: 10.1371/journal.pntd.0005426

The RNAi pathway plays a small part in Wolbachia-mediated blocking of dengue virus in mosquito cells.

Terradas, G., Joubert, D.A., McGraw, E.A. 2017. The RNAi pathway plays a small part in Wolbachia-mediated blocking of dengue virus in mosquito cells. Nature Scientific Reports 7. doi:10.1038/srep43847

Gut microbiota in Drosophila melanogaster interacts with Wolbachia but does not contribute to Wolbachia-mediated antiviral protection.

Yea, Y.H., Seleznev, A., Flores,  H.A., Woolfit, M., Elizabeth A.McGraw, E.A. 2016. Gut microbiota in Drosophila melanogaster interacts with Wolbachia but does not contribute to Wolbachia-mediated antiviral protection. Journal of Invertebrate Pathology 143, pp 18-25.  Doi: 10.1016/j.jip.2016.11.011

Wolbachia-Based Dengue Virus Inhibition Is Not Tissue-Specific in Aedes aegypti.

Amuzu,H.E., McGraw, E.A. 2016. Wolbachia-Based Dengue Virus Inhibition Is Not Tissue-Specific in Aedes aegypti. PLoS Neglected Tropical Diseases 10. Doi:10.1371/journal.pntd.0005145

Evolutionary potential of the extrinsic incubation period of dengue virus in Aedes aegypti.

Ye, Y. H., Chenoweth, S. F., Carrasco, A. M., Allen, S. L., Frentiu, F. D., van den Hurk, A. F., Beebe, N. W. and McGraw, E. A. (2016), Evolutionary potential of the extrinsic incubation period of dengue virus in Aedes aegypti. Evolution. Accepted Author Manuscript. Doi: 10.1111/evo.13039

The Effect of Temperature on Wolbachia-Mediated Dengue Virus Blocking in Aedes aegypti.

Ye, H. Y., Carrasco, A.M., Dong, Y. , Sgrò, C.M., McGraw, E.A. 2016. The Effect of Temperature on Wolbachia-Mediated Dengue Virus Blocking in Aedes aegypti. American Journal of Tropical Medicine and Hygiene vol. 94 no. 4 pp 812-819. Doi: 10.4269/ajtmh.15-0801

Assessing the epidemiological effect of wolbachia for dengue control

Lambrechts, L., Ferguson, N.M., Harris, E., Holmes, E.C., McGraw, E.A., O’Neill,  S.L., Ooi, E.E., Ritchie, S.A., Ryan, P.A., Scott, T.W., Simmons, C.P., Weaver, S.C. 2015. Assessing the epidemiological effect of wolbachia for dengue control. The Lancet Infectious Diseases. Doi: 10.1016/S1473-3099(15)00091-2

Effect of repeat human blood feeding on Wolbachia density and dengue virus infection in Aedes aegypti.

Amuzu, H.E, Simmons, C.P., McGraw, E.A. 2015. Effect of repeat human blood feeding on Wolbachia density and dengue virus infection in Aedes aegypti. Parasites & Vectors 8:246.  Doi:10.1186/s13071-015-0853-y

Modeling the impact on virus transmission of Wolbachia-mediated blocking of dengue virus infection of Aedes aegypti. 

Ferguson, N.M., Hue Kien, D.T., Clapham, H., Aguas, R., Trung, V.T., Bich Chau, T.N., Popovici, J., Ryan, P.A., O’Neill, S.L., McGraw, E.A., Long, V.T., Dui, L.T. , Nguyen, H.L., Vinh Chau, N.V., Wills, B., Simmons, C.P. 2015. Modeling the impact on virus transmission of Wolbachia-mediated blocking of dengue virus infection of Aedes aegypti. Sci. Transl. Med. 7,279ra37. Doi: 10.1126/scitranslmed.3010370

Discovery of Putative Small Non-Coding RNAs from the Obligate Intracellular Bacterium Wolbachia pipientis.

Woolfit M., Algama M., Keith J.M., McGraw E.A., Popovici J. 2015. Discovery of Putative Small Non-Coding RNAs from the Obligate Intracellular Bacterium Wolbachia pipientis. PLoS ONE 10(3): e0118595. Doi:10.1371/journal.pone.0118595

Wolbachia infection does not alter attraction of the mosquito Aedes aegypti to human odours.

Turley, A.P., Smallegange, R.C., Takken, W., Zalucki, M.P., O’Neill, S.L., McGraw, E.A. 2014.Wolbachia infection does not alter attraction of the mosquito Aedes aegypti to human odours. Med Vet Entomol in press. Doi: 10.1111/mve.12063.

The nature and extent of mutational pleiotropy in gene expression.

McGuigan, K., Collet, J., McGraw, E.A., Ye, Y.H., Allen, S.L., Chenoweth, S.F., Blows, M.W. 2014. The nature and extent of mutational pleiotropy in gene expression. Genetics 196:911-21. Doi:10.1534/genetics.114.161232

Limited dengue virus replication in field-collected Aedes aegypti mosquitoes infected with Wolbachia.

Frentiu, F.D., Zakir, T., Walker T., Popvici, J., Pyke A.T., van den Hurk, A., McGraw, E.A., O’Neill, S.L. 2014. Limited dengue virus replication in field-collected Aedes aegypti mosquitoes infected with Wolbachia.  PLoS Neglect Trop Dis 8:e2688. Doi:10.1371/journal.pntd.0002688

Wolbachia competes with its mosquito hosts for amino acids causing fecundity defects.

Caragata, E., Rances, E., O’Neill, S.L., McGraw, E.A., 2014. Wolbachia competes with its mosquito hosts for amino acids causing fecundity defects. Microbial Ecol 67:205-18. Doi:10.1007/s00248-013-0339-4

Comparative Oral Susceptibility of mosquito sub-populations in north Queensland, Australia to Oral Infection with dengue.

Ye, Y.H., Ng, T.S., Frentiu, F.D., Walker, T., Beebe, N.. O’Neill, S.L., McGraw E.A. 2014. Comparative Oral Susceptibility of mosquito sub-populations in north Queensland, Australia to Oral Infection with dengue. Am J Trop Med Hyg 90L422-30. Doi:10.4269/ajtmh.13-0186

Genomic evolution of the pathogenic Wolbachia strain,wMelPop.

Woolfit, M., Iturbe-Ormaetxe, I., Brownlie, J.C., Walker, T., Riegler, M., Seleznev, A., Popvici, J., Wee, B.A., Pavlides, J., Sullivan, M.J., Beatson, S.A., Lane, A., Sidhu, M., McMeniman, C.J.,McGraw, E.A., O’Neill, S.L. 2014. Genomic evolution of the pathogenic Wolbachia strain,wMelPop. Genome Biol Evol 5:2189-204. Doi:10.1093/gbe/evt169

Beyond insecticides: new thinking on an ancient problem.

McGraw, E.A., O’Neill, S.L., 2013, Beyond insecticides: new thinking on an ancient problem, Nature Reviews Microbiology [P], vol 11, issue 3, Nature Publishing Group, London England, pp. 181-193. Doi:10.1038/nrmicro2968

Dietary cholesterol modulates pathogen blocking by Wolbachia

Caragata, E.P., Rances, E., Hedges, L.M., Gofton, A., Johnson, K.N., O’Neill, S.L.,McGraw, E.A., 2013, Dietary cholesterol modulates pathogen blocking by Wolbachia, PLoS Pathogens [E], vol 9, issue 6, Public Library Science, United States, pp. 1-9. Doi:10.1371/journal.ppat.1003459

Draft genome sequence of the male-killing Wolbachia strain wBol1 reveals recent horizontal gene transfers from diverse sources.

Duplouy, A., Iturbe-Ormaeche, I., Beatson, S.A., Szubert, J.M., Brownlie, J.C., McMeniman, C.J., McGraw, E.A., Hurst, G.D.D., Charlat, S., O’Neill, S.L., Woolfit, M., 2013, Draft genome sequence of the male-killing Wolbachia strain wBol1 reveals recent horizontal gene transfers from diverse sources, BMC Genomics [P], vol 14, issue 20, Biomed Central Ltd, London England, pp. 1-13. Doi:10.1186/1471-2164-14-20

Infection with a virulent strain of Wolbachia disrupts genome wide-patterns of cytosine methylation in the mosquito Aedes aegypti.

Ye, Y., Woolfit, M., Huttley, G.A., Rances, E., Caragata, E.P., Popovici, J.O.O., O’Neill, S.L., McGraw, E.A., 2013, Infection with a virulent strain of Wolbachia disrupts genome wide-patterns of cytosine methylation in the mosquito Aedes aegypti, PLoS ONE [P], vol 8, issue 6, Public Library Science, San Francisco USA, pp. 1-9. Doi:10.1371/journal.pone.0066482

Transinfected Wolbachia have minimal effects on male reproductive success in Aedes aegypti.

Turley, A.P., Zalucki, M.P., O’Neill, S.L., McGraw, E.A., 2013, Transinfected Wolbachia have minimal effects on male reproductive success in Aedes aegypti, Parasites & Vectors [E], vol 6, issue 36, Biomed Central Ltd, London England, pp. 1-10. Doi:10.1186/1756-3305-6-36

Wolbachia-associated bacterial protection in the mosquito Aedes aegypti.

Ye, Y., Woolfit, M., Rances, E., O’Neill, S.L., McGraw, E.A., 2013, Wolbachia-associated bacterial protection in the mosquito Aedes aegypti, PL o S Neglected Tropical Diseases [E], vol 7, issue 8, Public Library Science, San Francisco USA, pp. 1-10. Doi:10.1371/journal.pntd.0002362

The relative importance of innate immune priming in Wolbachia-mediated dengue interference.

Rances, E., Ye, Y., Woolfit, M., McGraw, E.A., O’Neill, S.L., 2012, The relative importance of innate immune priming in Wolbachia-mediated dengue interference, Plos Pathogens [P], vol 8, issue 2, Public Library Science, San Francisco USA, pp. 1-10. Doi:10.1371/journal.ppat.1002548

Adult Drosophila melanogaster evolved for antibacterial defense invest infection-induced expression of both humoral and cellular immunity genes.

Ye, Y., McGraw, E.A., 2011, Adult Drosophila melanogaster evolved for antibacterial defense invest infection-induced expression of both humoral and cellular immunity genes,BMC Research Notes [E], vol 4, BioMed Central Ltd, United Kingdom, pp. 1-7. Doi:10.1186/1756-0500-4-305

High-dimensional variance partitioning reveals the modular genetic basis of adaptive divergence in gene expression during reproductive character displacement.

McGraw, E.A., Ye, Y., Foley, B., Chenoweth, S., Higgie, M., Hine, E., Blows, M., 2011, High-dimensional variance partitioning reveals the modular genetic basis of adaptive divergence in gene expression during reproductive character displacement, Evolution; international journal of organic evolution [P], vol 65, issue 11, Wiley-Blackwell, Malden USA, pp. 3126-3137. Doi:10.1111/j.1558-5646.2011.01371.x

Improved accuracy of the transcriptional profiling method of age grading in Aedes aegypti mosquitoes under laboratory and semi-field cage conditions and in the presence of Wolbachia infection.

Caragata, E.A., Poinsignon, A., Moreira, L., Johnson, P., Leong, Y., Ritchie, S., O’Neill, S.L., McGraw, E., 2011, Improved accuracy of the transcriptional profiling method of age grading in Aedes aegypti mosquitoes under laboratory and semi-field cage conditions and in the presence of Wolbachia infection, Insect Molecular Biology [P], vol 20, issue 2, Wiley-Blackwell, Malden USA, pp. 215-224. Doi:10.1111/j.1365-2583.2010.01059.x

Successful establishment of Wolbachia in Aedes populations to suppress dengue transmission.

Hoffmann, A., Montgomery, B., Popovici, J., Iturbe-Ormaeche, I., Johnson, P., Muzzi, F., Greenfield, M., Durkan, M., Leong, Y., Dong, Y., Cook, H., Axford, J., Callahan, A., Kenny, N., Omodei, C., McGraw, E.A., Ryan, P., Ritchie, S., Turelli, M., O’Neill, S.L., 2011, Successful establishment of Wolbachia in Aedes populations to suppress dengue transmission, Nature [P], vol 476, issue 7361, Nature Publishing Group, England, pp. 454-459. Doi:10.1038/nature10356

The wMelPop strain of Wolbachia interferes with dopamine levels in Aedes aegypti.

Moreira, L., Ye, Y., Turner, K., Eyles, D., McGraw, E.A., O’Neill, S.L., 2011, The wMelPop strain of Wolbachia interferes with dopamine levels in Aedes aegypti, Parasites & Vectors [E], vol 4, issue 28, Biomed Central Ltd, London England, pp. 1-5. Doi:10.1186/1756-3305-4-28

Variable infection frequency and high diversity of multiple strains of Wolbachia pipientis in Perkinsiella Planthoppers.

Hughes, G., Allsopp, P., Brumbley, S., Woolfit, M., McGraw, E.A., O’Neill, S.L., 2011, Variable infection frequency and high diversity of multiple strains of Wolbachia pipientis in Perkinsiella Planthoppers, Applied And Environmental Microbiology [P], vol 77, issue 6, The American Society for Microbiology, Washington USA, pp. 2165-2168. Doi: 10.1128/AEM.02878-10

Wolbachia infection increases recapture rate of field-released Drosophila melanogaster.

Caragata, E., Real, K., Zalucki, M., McGraw, E., 2011, Wolbachia infection increases recapture rate of field-released Drosophila melanogaster, Symbiosis [P], vol 54, issue 1, Springer, Dordrecht Netherlands, pp. 55-60. Doi:10.1007/s13199-011-0124-4

Fruit fly bioassay to distinguish “sweet” sugar structures.

Hodoniczky, J., Robinson, G., McGraw, E., Rae, A., 2010, Fruit fly bioassay to distinguish “sweet” sugar structures, Journal of Agricultural and Food Chemistry [P], vol 58, issue 24, American Chemical Society, Washington USA, pp. 12885-12889. Doi:10.1021/jf102458b

Wolbachia pipientis: an expanding bag of tricks to explore for disease control.

Cook, P., McGraw, E., 2010, Wolbachia pipientis: an expanding bag of tricks to explore for disease control, Trends in Parasitology [P], vol 26, issue 8, Elsevier Science Ltd, Oxon England, pp. 373-375. Doi:10.1016/j.pt.2010.05.006

Wolbachia-mediated resistance to dengue virus infection and death at the cellular level.

Frentiu, F., Robinson, J., Young, P., McGraw, E., O’Neill, S.L., 2010, Wolbachia-mediated resistance to dengue virus infection and death at the cellular level, PLoS ONE [P], vol 5, issue 10, Public Library Science, San Diego USA, pp. 1-8. Doi:10.1371/journal.pone.0013398

A Wolbachia symbiont in Aedes Aegypti limits infection with dengue, chikungunya, and plasmodium.

Moreira, L., Iturbe-Ormaetxe, I., Jeffery, J., Lu, G., Pyke, A., Hedges, L., Rocha, B., Hall-Mendelin, S., Day, A., Riegler, M., Hugo, L., Johnson, K., Kay, B., McGraw, E., van der Hurk, A., Rayn, P., O’Neill, S.L., 2009, A Wolbachia symbiont in Aedes Aegypti limits infection with dengue, chikungunya, and plasmodium, Cell [P], vol 139, issue 7, Cell Press, Cambridge USA, pp. 1268-1278. Doi:10.1016/j.cell.2009.11.042

An ancient horizontal gene transfer between mosquito and the endosymbiotic bacterium Wolbachia pipientis.

Woolfit, M., Iturbe-Ormaetxe, I., McGraw, E., O’Neill, S.L., 2009, An ancient horizontal gene transfer between mosquito and the endosymbiotic bacterium Wolbachia pipientis, Molecular Biology And Evolution [P], vol 26, issue 2, Oxford University Press, Oxford England, pp. 367-374. Doi:10.1093/molbev/msn253

An expressed sequence tag (EST) library for Drosophila serrata, a model system for sexual selection and climatic adaptation studies

Frentiu, F., Adamski, M., McGraw, E., Blows, M., Chenoweth, S., 2009, An expressed sequence tag (EST) library for Drosophila serrata, a model system for sexual selection and climatic adaptation studies, BMC Genomics [P], vol 10, issue 40, Biomedical Central Ltd, London England, pp. 1-10. Doi:10.1186/1471-2164-10-40

Effective but costly, evolved mechanisms of defense against a virulent opportunistic pathogen in Drosophila melanogaster

Ye, Y., Chenoweth, S., McGraw, E., 2009, Effective but costly, evolved mechanisms of defense against a virulent opportunistic pathogen in Drosophila melanogaster, Plos Pathogens [P], vol 5, issue 4, Public Library Science, San Francisco USA, pp. 1-9. Doi:10.1371/journal.ppat.1000385

Evidence for metabolic provisioning by a common invertebrate endosymbiont, Wolbachia pipientis, during periods of nutritional stress

Brownlie, J., Cass, B., Riegler, M., Witsenburg, J., Iturbe-Ormaetxe, I., McGraw, E., O’Neill, S.L., 2009, Evidence for metabolic provisioning by a common invertebrate endosymbiont, Wolbachia pipientis, during periods of nutritional stress, Plos Pathogens [P], vol 5, issue 4, Public Library Science, San Francisco USA, pp. 1-6. Doi:10.1371/journal.ppat.1000368

Human probing behavior of Aedes aegypti when infected with a life-shortening strain of Wolbachia.

Moreira, L., Saig, E., Turley, A., Ribeiro, J., O’Neill, S.L., McGraw, E., 2009, Human probing behavior of Aedes aegypti when infected with a life-shortening strain of Wolbachia, Public Library of science: Neglected Tropical Diseases [P], vol 3, issue 12, Public Library Science, San Francisco USA, pp. 1-6. Doi:10.1371/journal.pntd.0000568

Increased locomotor activity and metabolism of Aedes aegypti infected with a lifeshortening strain of Wolbachia pipientis.

Evans, O., Caragata, E., McMeniman, C., Woolfit, M., Green, D., Williams, C., Franklin, C., O’Neill, S.L., McGraw, E., 2009, Increased locomotor activity and metabolism of Aedes aegypti infected with a lifeshortening strain of Wolbachia pipientis, Journal Of Experimental Biology [P], vol 212, issue 10, The Company of Biologists Ltd, Cambridge England, pp. 1436-1441. Doi:10.1242/jeb.028951

The ecological differentiation of asexual lineages of cotton aphids: alate behaviour, sensory physiology, and differential host associations.

Najar-Rodriguez, A., McGraw, E., Hull, C., Mensah, R., Walter, G., 2009, The ecological differentiation of asexual lineages of cotton aphids: alate behaviour, sensory physiology, and differential host associations, Biological Journal Of The Linnean Society [P], vol 97, issue 3, Wiley-Blackwell, Malden USA, pp. 503-519. Doi:10.1111/j.1095-8312.2009.01235.x

The microbial flora of Aphis gossypii: patterns across plants and geographical space.

Najar-Rodriguez, A., McGraw, E., Mensah, R., Pittman, G., Walter, G., 2009, The microbial flora of Aphis gossypii: patterns across plants and geographical space, Journal Of Invertebrate Pathology [P], vol 100, issue 2, Academic Press Inc Elsevier Science, San Diego USA, pp. 123-126. Doi:10.1016/j.jip.2008.10.005

Wolbachia infection in Australasian and North American populations of Haematobia irritans (Diptera: Muscidae)

Zhang, B., McGraw, E., Floate, K., James, P., Jorgensen, W., Rothwell, J., 2009, Wolbachia infection in Australasian and North American populations of Haematobia irritans (Diptera: Muscidae), Veterinary Parasitology [P], vol 162, issue 3-4, Elsevier Science, Amsterdam Netherlands, pp. 350-353. Doi:10.1016/j.vetpar.2009.03.012

Wolbachia infection reduces blood-feeding success in the dengue fever mosquito, Aedes aegypti.

Turley, A., Moreira, L., O’Neill, S.L., McGraw, E., 2009, Wolbachia infection reduces blood-feeding success in the dengue fever mosquito, Aedes aegypti, Public Library of science: Neglected Tropical Diseases [P], vol 3, issue 9, Public Library Science, San Francisco USA, pp. 1-6. Doi:10.1371/journal.pntd.0000516

Drosophila melanogaster mounts a unique immune response to the rhabdovirus Sigma virus.

Tsai, C., McGraw, E., Ammar, E., Dietzgen, R., Hogenhout, S., 2008, Drosophila melanogaster mounts a unique immune response to the rhabdovirus Sigma virus, Applied And Environmental Microbiology [P], vol 74, issue 10, American Society of Microbiology, Washington USA, pp. 3251-3256. Doi:10.1128/AEM.02248-07

Host adaptation of a Wolbachia strain after long-term serial passage in mosquito cell lines.

McMeniman, C., Lane, A., Fong, A., Voronin, D., Iturbe-Ormaetxe, I., Yamada, R., McGraw, E., O’Neill, S.L., 2008, Host adaptation of a Wolbachia strain after long-term serial passage in mosquito cell lines, Applied And Environmental Microbiology [P], vol 74, issue 22, American Society of Microbiology, Washington DC USA, pp. 6963-6969. Doi:10.1128/AEM.01038-08

Wolbachia infection alters olfactory-cued locomotion in Drosophila spp.

Peng, Y., Nielsen, J., Cunningham, P., McGraw, E., 2008, Wolbachia infection alters olfactory-cued locomotion in Drosophila spp., Applied And Environmental Microbiology [P], vol 74, issue 13, America Society of Microbiology, Washington USA, pp. 3943-3948. Doi:10.1128/AEM.02607-07

Diversifying selection and host adaptation in two endosymbiont genomes.

Brownlie, J., Adamski, M., Slatko, B., McGraw, E., 2007, Diversifying selection and host adaptation in two endosymbiont genomes, BMC Evolutionary Biology [P], vol 7, issue 68, Biomed Central Ltd, London England, pp. 1-12. Doi:10.1186/1471-2148-7-68

Wolbachia: Invasion biology in South Pacific butterflies.

McGraw, E., O’Neill, S.L., 2007, Wolbachia: Invasion biology in South Pacific butterflies,Current Biology [P], vol 17, issue 6, Cell Press, Cambridge USA, pp. R220-R221. Doi:10.1016/j.cub.2007.01.038

Parasitic castration by the digenian trematode Allopodocotyle sp. alters gene expression in the brain of the host mollusc Haliotis asinina

Rice, T., McGraw, E., O’Brien, E., Reverter, A., Jackson, D., Degnan, B., 2006, Parasitic castration by the digenian trematode Allopodocotyle sp. alters gene expression in the brain of the host mollusc Haliotis asinina, FEBS Letters [P], vol 580, issue 15, Elsevier Science, Amsterdam Netherlands, pp. 3769-3774. Doi:10.1016/j.febslet.2006.05.068

Evidence of a spotted fever-like rickettsia and a potential new vector from northeastern Australia.

Lane, A., Shaw, M., McGraw, E., O’Neill, S.L., 2005, Evidence of a spotted fever-like rickettsia and a potential new vector from northeastern Australia, Journal of Medical Entomology [P], vol 42, issue 5, Entomological Society of America, Lanham USA, pp. 918-921. Doi:10.1603/0022-2585(2005)042[0918:EOASFR]2.0.CO;2

Ultraconserved elements in insect genomes: A highly conserved intronic sequence implicated in the control of homothorax mRNA splicing.

Glazov, E., Pheasant, M., McGraw, E., Bejerano, G., Mattick, J., 2005, Ultraconserved elements in insect genomes: A highly conserved intronic sequence implicated in the control of homothorax mRNA splicing, Genome Research [P], vol 15, issue 6, Cold Spring Harbor Laboratory Press, Woodbury USA, pp. 800-808

Phylogenomics of the reproductive parasite Wolbachia pipientis wMel: A streamlined genome overrun by mobile genetic elements.

Wu, M., Sun, L., Vamathevan, J., Riegler, M., DeBoy, R., Brownlie, J., McGraw, E., Martin, W., Esser, C., Ahmadinejad, N., Wiegand, C., Madupu, R., Beanan, M., Brinkac, L., Daugherty, S., Durkin, A., Kolonay, J., Nelson, W., Mohamoud, Y., Lee, P., Berry, K., Young, M., Utterback, T., Wiedman, J., Nierman, W., Paulsen, I., Nelson, K., Tettelin, H., O’Neill, S.L., Eisen, J., 2004, Phylogenomics of the reproductive parasite Wolbachia pipientis wMel: A streamlined genome overrun by mobile genetic elements, Plos Biology [P], vol 2, issue 3, Public Library Science, San Francisco USA, pp. 327-341. Doi:10.1371/journal.pbio.0020069

Wolbachia pipientis in Australian spiders.

Rowley, S., Raven, R., McGraw, E., 2004, Wolbachia pipientis in Australian spiders,Current Microbiology [P], vol 49, issue 3, Springer, New York USA, pp. 208-214. Doi:10.1007/s00284-004-4346-z

Wolbachia pipientis: intracellular infection and pathogenesis in Drosophila.

McGraw, E., O’Neill, S.L., 2004, Wolbachia pipientis: intracellular infection and pathogenesis in Drosophila, Current Opinion in Microbiology [P], vol 7, issue 1, Current Biology Ltd, London England, pp. 67-70. Doi:10.1016/j.mib.2003.12.003

Wolbachia replication and host cell division in Aedes albopictus.

Ruang-Areerate, T., Kittayapong, P., McGraw, E., Baimai, V., O’Neill, S.L., 2004, Wolbachia replication and host cell division in Aedes albopictus, Current Microbiology [P], vol 49, issue 1, Springer, New York USA, pp. 10-12. Doi:10.1007/s00284-003-4245-8

Sequence polymorphism of dotA and mip alleles mediating invasion and intracellular replication of Legionella pneumophila.

Bumbaugh, A., McGraw, E., Page, K., Selander, R., Whittam, T., 2002, Sequence polymorphism of dotA and mip alleles mediating invasion and intracellular replication of Legionella pneumophila, Current Microbiology [P], vol 44, issue 5, Springer, New York USA, pp. 314-322. Doi:10.1007/s00284-01-0024-6

Wolbachia density and virulence attenuation after transfer into a novel host.

McGraw, E., Merritt, D., Droller, J., O’Neill, S.L., 2002, Wolbachia density and virulence attenuation after transfer into a novel host, Proceedings Of The National Academy Of Sciences Of The United States Of America [P], vol 99, issue 5, National Academy of Sciences, Washington USA, pp. 2918-2923. Doi:10.1073/pnas.052466499

Wolbachia-mediated sperm modification is dependent on the host genotype in Drosophila.

McGraw, E., Merritt, D., Droller, J., O’Neill, S.L., 2001, Wolbachia-mediated sperm modification is dependent on the host genotype in Drosophila, Proceedings of the Royal Society – Biological Sciences (Series B) [P], vol 268, issue 1485, Royal Society of London, London England, pp. 2565-2570. Doi:10.1098/rspb.2001.1839

Clonal relationship among invasive and non-invasive strains of enteroinvasive Escherichia coli serogroups.

Martinez, M., Whittan, T., McGraw, E., Rodrigues, J., Trabulsi, L., 1999, Clonal relationship among invasive and non-invasive strains of enteroinvasive Escherichia coli serogroups,FEMS Microbiology Letters [P], vol 172, issue 2, Elsevier Science, Amsterdam Netherlands, pp. 145-151. Doi:10.1111/j.1574-6968.1999.tb13462.x

Evolution of Wolbachia pipientis transmission dynamics in insects.

McGraw, E., O’Neill, S.L., 1999, Evolution of Wolbachia pipientis transmission dynamics in insects, Trends in Microbiology [P], vol 7, issue 7, Elsevier Science, London England, pp. 297-302. Doi:10.1016/S0966-842X(99)01531-0

Molecular evolution and mosaic structure of alpha, beta, and gamma intimins of pathogenic Escherichia coli.

McGraw, E., Li, J., Selander, R., Whittam, T., 1999, Molecular evolution and mosaic structure of alpha, beta, and gamma intimins of pathogenic Escherichia coli, Molecular Biology And Evolution [P], vol 16, issue 1, Oxford University Press, Oxford England, pp. 12-22.